Sillajen presents ‘BAL0891’ research findings at Asian Oncology Society and Korean 해외 바카라사이트 Association conference

Professor Rha Sun-young's research team at Yonsei University identifies gastric 해외 바카라사이트 biomarker candidates using patient-derived organoids

2025-07-09Ji, 해외 바카라사이트 Jun
Source: 해외 바카라사이트

[by Ji, Yong Jun] Sillajen announced on July 8 that the research team led by Professor Rha Sun-young from the Department of Oncology at Yonsei Severance Hospital presented research findings on its anti해외 바카라사이트 pipeline, ‘BAL0891,’ at the joint academic conference of the ‘5th Asian Oncology Society (AOS 2025)’ and the ‘51st Korean 해외 바카라사이트 Association.’

The Asian Oncology Society (AOS) is the largest international 해외 바카라사이트 conference in Asia. This year’s event was held over two days starting on July 3 at COEX in Samseong-dong, Seoul, under the auspices of the Korean 해외 바카라사이트 Association. The next conference is scheduled to take place in Kobe, Japan, next year.

The study presented at the conference evaluated the anti해외 바카라사이트 efficacy and precision medicine potential of BAL0891 using patient-derived organoids obtained from malignant ascites in patients with advanced gastric 해외 바카라사이트. Peritoneal metastasis accompanied by malignant ascites in advanced gastric 해외 바카라사이트 represents a high-risk disease with limited treatment options and poor survival rates, underscoring the urgent need for effective therapeutic strategies. Through this study, the research team demonstrated the potential of BAL0891 as a novel treatment option and explored approaches to address existing unmet medical needs.

The study demonstrated that BAL0891 exhibited a significant 해외 바카라사이트 cell inhibition effect in the gastric 해외 바카라사이트 organoid model. Furthermore, specific protein expression patterns were consistently observed in models that responded to the treatment. Based on these findings, the research team identified a set of potential biomarker candidates that may be used to predict future drug responses.

In particular, this study employed proteomic analysis to identify differential expression of 14 key proteins involved in pathways essential to 해외 바카라사이트 cell survival, including the cell cycle, DNA replication, RNA degradation, and DNA damage repair, that were associated with responsiveness to BAL0891. Although the basal expression level of BAL0891’s direct target protein did not show a clear correlation with drug sensitivity, the company noted that the identification of alternative biomarker candidates linked to drug responsiveness holds meaningful clinical relevance.

Looking ahead, these 해외 바카라사이트 are expected to serve as a valuable foundation for patient selection and the development of personalized treatment strategies based on precision medicine. Additionally, they may offer a scientific rationale for the development of combination therapies aimed at patients who do not respond to drugs.

“This study is significant in that it established a platform capable of not only demonstrating the anti해외 바카라사이트 efficacy of BAL0891 but also identifying biomarker candidates applicable to real-world clinical trials using a model derived from patients with advanced gastric 해외 바카라사이트,” a company official said. “This will be a turning point for fully implementing a solid tumor treatment strategy grounded in precision medicine.”